Can I dissolve clarithromycin in water?

Solubility: Clarithromycin is soluble in acetone, slightly soluble in methanol, ethanol, and acetonitrile, and practically insoluble in water [FDA label]. Water solubility 0.33 mg/l [DrugBank]. Polarity: Log P 2.69 [DrugBank].

Can you crush antibiotics and put in food?

“Don’t rush to crush” Mixing the contents of a capsule with food or adding a crushed tablet to a drink may seem a better option than asking your doctor or nurse to change a prescription to a more suitable format such as a Liquid Medicine.

Can you eat dairy with clarithromycin?

You may take clarithromycin with meals or milk or on an empty stomach. However, clarithromycin extended release tablets should be taken with food.

Can you take the powder out of antibiotic capsules?

The NHS advise that you shouldn’t chew, crush and break tablets, or open and empty powder out of capsules, unless your doctor or another healthcare professional has told you to do so.

What happens if you crush clarithromycin?

If you are using the extended-release tablets: Swallow the tablet whole. Do not break, crush, or chew it. While taking the extended-release form of this medicine, a part of the tablet may pass into your stools.

Can you take crushed tablets with yogurt?

Even if the pill can be mixed with food, you may be advised to take it with only a small amount of soft food. While sprinkling it over a bowl of yogurt or porridge may help erase any bitter taste, you can end up losing a lot of the drug if you don’t finish the bowl and scrape the bottom completely.

Can antibiotics be dissolved in water?

All the antibiotics have the same solubility order; that is, they are more soluble in water than in ethanol, and more soluble in ethanol than in 2-propanol and acetone. The solubility in water is ∼3 orders of magnitude higher than that in acetone.

Can we dissolve tablets in water?

As the pills or capsules dissolve in the bottle of water, they may change appearance. Shortly after entering the water in the bottle, the pills or capsules may no longer be recognizable by the consumer. For example, the capsules (made of a type of gelatin) begin to swell in the water.

Can you crush clarithromycin?

Swallow the tablet whole. Do not break, crush, or chew it. While taking the extended-release form of this medicine, a part of the tablet may pass into your stools. This is normal and is nothing to worry about.

Can you take clarithromycin with juice?

Clarithromycin 250 mg/5 ml Oral Suspension should be administered twice daily as recommended in the table above. The doses should be given at 12-hour intervals. Clarithromycin oral suspension can cause a bitter after-taste. This can be avoided by drinking juice or water soon after intake of the suspension.

What happens if you crush a capsule?

Crushing them can change the rate of release and lead to temporary overdose. Pills which are taken just once a day often have a special coating which makes the release into the body slow and constant during the 24-hour period.

What happens if you stop Taking clarithromycin too early?

If you stop your treatment early, your infection could come back. Clarithromycin tablets come in 250mg or 500mg strengths. Swallow clarithromycin tablets or capsules whole with a drink of water, with or without food. Do not chew or break them. Clarithromycin granules come in 250mg sachets.

Can clarithromycin be given over the counter?

Clarithromycin is only available on prescription. It comes as tablets, granules, or a liquid that you drink. It can also be given by injection, but this is usually only done in hospital. 2. Key facts It’s usual to take clarithromycin twice a day: once in the morning and once in the evening.

How should I take clarithromycin and zidovudine?

The average household teaspoon may not hold the right amount of liquid. Shake the bottle well before each use. If you are taking clarithromycin and zidovudine, these medicines should be taken at least 2 hours apart. Keep using this medicine for the full time of treatment, even if you or your child begin to feel better after the first few doses.

Is there a liquid version of clarithromycin for children?

There’s also a liquid clarithromycin for children and people who find it difficult to swallow tablets. If you or your child are taking clarithromycin as a liquid, your pharmacist will usually make it up for you. The medicine will come with a plastic syringe or spoon to help you take the right amount.