Does Clemmensen reduce double bond?

The Clemmensen Reduction involves adding Zn(Hg) dissolved in heated HCl to something reducible. Note though that this process can accidentally chlorinate a double bond also present on the reactant. At that point a hydrochlorination would happen across the double bond, forming an alkyl chloride.

What type of reaction is Clemmensen reduction?

Clemmensen reduction is a chemical reaction described as a reduction of ketones (or aldehydes) to alkanes using zinc amalgam and concentrated hydrochloric acid. This reaction is named after Erik Christian Clemmensen, a Danish chemist.

What is Zn Hg HCl?

The reaction of aldehydes and ketones with zinc amalgam (Zn/Hg alloy) in concentrated hydrochloric acid, which reduces the aldehyde or ketone to a hydrocarbon, is called Clemmensen reduction.

What does Clemmensen reduction reduce?

Clemmensen reduction is a chemical reaction described as a reduction of ketones (or aldehydes) to alkanes using zinc amalgam and hydrochloric acid. The Clemmensen reduction is particularly effective at reducing aryl-alkyl ketones, such as those formed in a Friedel-Crafts acylation.

Does Clemmensen reduction reduce nitro group?

Zn−Hg/HCl has reduced both the ketonic and nitro group.

How does Clemmensen reduction work?

The Clemmensen Reduction allows the deoxygenation of aldehydes or ketones, to produce the corresponding hydrocarbon. The substrate must be stable to strong acid. The Clemmensen Reduction is complementary to the Wolff-Kishner Reduction, which is run under strongly basic conditions.

Does Clemmensen reduction work on carboxylic acid?

Also, Carboxylic acid (-COOH) group can’t be reduced by this method (but the -COOH group can be reduced by treating it with soda lime [NaOH+ CaO] and then heating). This mechanism employs the intermediacy of zinc carbenoids to rationalize the mechanism of the Clemmensen Reduction.

Why is zinc amalgamated in Clemmensen reduction?

The zinc amalgam is used in Clemmensen Reduction as the reaction of zinc with hydrochloric acid releases hydrogen gas (H₂). In this way, zinc amalgam acts to trap the active H₂ gas as it is formed, and it also allows to attack the carbonyl compound rather than it released H₂ gas.

Which reducing agent is used in Clemmensen reduction?

This Clemmensen reduction reaction is carried by using Zinc amalgam (Zn-Hg) and Hydrochloric acid (HCl) which is often referred to as Clemmensen’s reducing agent.

Does Clemmensen reduction reduce carboxylic acids?

Clemmensen reduction is an organic reduction reaction shown by both aldehydes and ketones. Also, Carboxylic acid (-COOH) group can’t be reduced by this method (but the -COOH group can be reduced by treating it with soda lime [NaOH+ CaO] and then heating). …

What reaction do nitro compounds undergo when treated with reducing agent?

The most important reaction of aromatic nitro compounds is their reduction, which can be brought about by a wide variety of agents. Under acidic conditions, reduction almost always produces an amine. In neutral media, reduction may yield a hydroxylamine.

What is the product of Clemmensen reduction?

Reduction of ketones (or aldehydes) to alkanes using zinc amalgam and hydrochloric acid.