What are the side effects of long term use of chlorpheniramine?

Nearly all patients treated with chlorpheniramine experience drowsiness. This drowsiness may subside in some patients with extended use. Few cases of dyskinesias and tremors, often of the face, have been reported in patients whose chronic use of chlorpheniramine extended over a period of 3 to 10 years.

How long does phenylephrine side effects last?

6. Response and effectiveness. The decongestant effect of phenylephrine in cold or flu remedies should be noticeable within 15 to 30 minutes, and the effects last less than 4 hours.

How do you treat drug toxicity?

If the toxicity is the result of an acute overdose, then a person may undergo stomach pumping to remove drugs that have not yet been absorbed. Activated charcoal may be given to bind the drugs and prevent them from being absorbed into the blood (instead, it is eliminated from the body through stool).

Can you overdose on chlorpheniramine maleate?

If you take too much (overdose) Symptoms of overdose of chlorphenamine include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations and possible seizures.

How many mg of chlorpheniramine maleate is fatal?

The estimated lethal dose of chlorphenamine is 25 to 50mg/kg body weight. Symptoms and signs include sedation, paradoxical excitation of the CNS, toxic psychosis, convulsions, apnoea, anticholinergic effects, dystonic reactions and cardiovascular collapse including arrhythmias.

Why was chlorpheniramine discontinued?

The antihistamine effects of chlorpheniramine account for its effect of reducing allergy symptoms. Brand name and generic formulations of combination products containing only chlorpheniramine and pseudoephedrine have been discontinued in the U. S., most likely due to the regulation of pseudoephedrine distribution.

What happens if you take too much phenylephrine?

Symptoms of overdose may include: severe dizziness/fainting, hallucinations, fast/irregular heartbeat, slow/shallow breathing, vomiting, seizures. If this product has been prescribed, do not share this medication with others. This medication is for temporary use only.

How much phenylephrine is too much?

Do not take more than 4 doses in 24 hours. If your symptoms do not go away talk to your doctor or pharmacist. Do not take for more than 7 days unless your doctor tells you to.

What are the symptoms of toxicity in the body?

Symptoms of toxicity can be varied and may include: poor circulation, swelling, headaches, migraines, stress, anxiety, depression, allergies, poor skin, yeast, arthritis, fatigue, constipation, obesity, cellulite, sinus issues, gout, digestive disorders, cold/respiratory disorders, insomnia, bloating, and gas.

What is toxic overload in the body?

Functional doctors use their skills to identify and correct possible toxin overload when treating patients. Accumulation of toxins within the body can cause endocrine (hormone) disruption and inflammatory dysregulation which can then alter the chemical messengers your body relies on to carry out proper immune function.

Can you OD on phenylephrine?

Does chlorpheniramine affect blood pressure?

Treatment with pseudoephedrine produced significant effects on all the four variables measured (systolic, diastolic and mean arterial blood pressure, and heart rate). Effects of the chlorpheniramine/paracetamol combination were found to be not significantly different from placebo.

What should I do if I overdose on phenylephrine?

Get emergency help immediately if any of the following symptoms of overdose occur while taking phenylephrine: Some side effects of phenylephrine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

What are the possible side effects of phenylephrine?

Phenylephrine Side Effects 1 Incidence Not Known. 2 Symptoms of Overdose. Some side effects of phenylephrine may occur that usually do not need medical… 3 Nervous system. Nervous system side effects have included headache, dizziness, nervousness,… 4 Cardiovascular. Cardiovascular side effects have included palpitations, arrhythmias,…

How long can you use phenylephrine HCl spray?

How to use Phenylephrine Hcl Spray, Non-Aerosol. This medication provides only temporary relief. Do not use more often, use more sprays, or use longer than directed because doing so may increase the risk of side effects. Also, do not use this medication for more than 3 days or it may cause a condition called rebound congestion.

What is phenylephrine and chlorpheniramine used for?

Chlorpheniramine-Phenylephrine Elixir. This combination medication is used to temporarily relieve symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis). Antihistamines help relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.